With unrelenting SARS-CoV-2 variants, additional COVID-19 mitigation strategies are needed. Oral and nasal saline irrigation (SI) is a traditional approach f...

Researching COVID to Enhance Recovery (RECOVER), a National Institutes of Health (NIH) research initiative, seeks to understand and prevent Long COVID

A covid mitigation tools library

Our last blog covered a study showing that intense exercise messes with the mitochondria, inhibits energy production, and can even produce muscle damage in some people with long COVID. Is all exercise necessarily bad, though? ME/CFS experts, and now David Putrino in long COVID, have produced gentler exercise programs that, […]

Games uniquely incorporate emotional and social factors that influence how we take in information — making them surprisingly useful communication tools in a world in denial about the ongoing threats of COVID-19 and Long COVID. Whether through the cathartic storytelling in indie designers’ interactive theater projects or learning opportunities woven into popular video games, playing games can help people make informed decisions amid the Long COVID crisis.

Long Covid Awareness Day March 15
Long Covid awareness ribbon gray/teal/black
International Long Covid Awareness Day

There are many reasons we seek in-person connections, including family and life events, holiday parties, celebrations, social gatherings, work or volunteer ...

The OpenERV is a ductless ERV, also called a decentralized or push-pull type. 

Introduction: Recent evidence suggests that oxidative stress and endothelial dysfunction play critical roles in the pathophysiology of COVID-19 and Long-COVID. We hypothesized that a supplementation combining L-Arginine (to improve endothelial function) and Vitamin C (to reduce oxidation) could have favorable effects on Long-COVID symptoms.

Methods: We designed a survey (LINCOLN: L-Arginine and Vitamin C improves Long-COVID), assessing several symptoms that have been associated with Long-COVID to be administered nationwide to COVID-19 survivors; the survey also included effort perception, measured using the Borg scale. Patients receiving the survey were divided in two groups, with a 2:1 ratio: the first group included patients that received L-Arginine + Vitamin C, whereas the second group received a multivitamin combination (alternative treatment).

Results: 1390 patients successfully completed the survey. Following a 30-day treatment in both groups, the survey revealed that patients in the L-Arginine + Vitamin C treatment arm had significantly lower scores compared to patients who had received the multivitamin combination. There were no other significant differences between the two groups. When examining effort perception, we observed a significantly lower value (p < 0.0001) in patients receiving L-Arginine + Vitamin C compared to the alternative-treatment arm.

Conclusions: Our survey indicates that the supplementation with L-Arginine + Vitamin C has beneficial effects in Long-COVID, in terms of attenuating its typical symptoms and improving effort perception.